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Antigenic Specificity | Human Fas apoptotic inhibitory molecule 3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation. |
Immunogen | Immunogen: Recombinant human Fas apoptotic inhibitory molecule 3 protein (18-251aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-8263 |
Other Names | [Regulator of Fas-induced apoptosis Toso; FAIM3; TOSO], [FCMR; FCMR; TOSO; FAIM3] |
Gene, Accession # | [FAIM3], Gene ID: 9214, NCBI: NP_001135945.1, UniProt: O60667 |
Catalog # | MBS1496626 |
Price | $120, $160 |
Order / More Info | Human Fas apoptotic inhibitory molecule 3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |