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Antigenic Specificity | Phospho-ESR1 (S118) |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial association with multiprotein coactivator complexes through LXXLL motifs of their respective components. Mutual transrepression occurs between the estrogen receptor (ER) and NF-ka |
Immunogen | Immunogen: A synthesized peptide derived from human Phospho-ESR1 (S118) |
Other Names | [Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1; ESR1; ESR; NR3A1] |
Gene, Accession # | [ESR1], Gene ID: 2099, NCBI: NP_000116.2, UniProt: P03372 |
Catalog # | MBS7114813 |
Price | $185, $265 |
Order / More Info | Phospho-ESR1 (S118) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |