Edit |   |
---|---|
Antigenic Specificity | PTAFR - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes. Binding of PAF to the PAF-receptor (PAFR) stimulates numerous signal transduction pathways including phospholipase C, D, A2, mitogen-activated protein kinases (MAPKs), and the phosphatidylinositol-calcium second messenger system. Following PAFR activation, cells become rapidly desensitized and this refractory state is dependent on PAFR phosphorylation, internalization, a |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PTAFR |
Other Names | [platelet-activating factor receptor; Platelet-activating factor receptor; platelet-activating factor receptor; platelet activating factor receptor] |
Gene, Accession # | [PTAFR], Gene ID: 5724, NCBI: NP_000943.1, UniProt: P25105 |
Catalog # | MBS3220385 |
Price | $335 |
Order / More Info | PTAFR - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |