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Antigenic Specificity | CUEDC2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for CUE domain-containing protein 2(CUEDC2) detection. Tested with WB, IHC-P in Human, Mouse, Rat. Background: CUEDC2(Cue Domain-Containing Protein 2) is involved in ubiquitin-and proteasome-mediated degradation of progesterone receptor(PR, or PGR) and estrogen receptor(ER)-alpha. Hartz(2011) mapped the CUEDC2 gene to chromosome 10q24.32 based on an alignment of the CUEDC2 sequence with the genomic sequence(GRCh37). Using coimmunoprecipitation analysis and protein pull-down assays, Zhang et al.(2007) confirmed that CUEDC2 interacted with the PRB isoform of PR. Mutation analysis revealed that the IF domain of PRB and the CUE domain of CUEDC2 were required for the interaction. CUEDC2 reduced PRB pro |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human CUEDC2 (267-287aa EAEEMKATYINLKPARKYRFH), identical to the related mouse sequence, and different from the related rat sequence by one amino acid. |
Other Names | [CUE domain-containing protein 2; CUE domain containing 2; bA18I14.5; C10orf66; Chromosome 10 open reading frame 66; CUE domain containing 2; CUE domain-containing protein 2; CUED2; CUED2_HUMAN; Cuedc2; MGC2491; OTTHUMP00000020368], [CUEDC2; CUEDC2; C10orf66; bA18I14.5; C10orf66] |
Gene, Accession # | [CUEDC2], Gene ID: 79004, NCBI: Q9H467.1, UniProt: Q9H467 |
Catalog # | MBS176042 |
Price | $315 |
Order / More Info | CUEDC2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |