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Antigenic Specificity | TNFAIP8L2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TNFAIP8L2 antibody detects endogenous levels of total TNFAIP8L2. Function: Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis (By similarity).Subunit Structure: May interact with CASP8; however, such result is unclear since PubMed:19079267 could not reproduce the interaction with CASP8.Similarity: The central region was initially thought to constitute a DED (death effector) domain. However, 3D-structure data reveal a previously uncharacterized fold t |
Immunogen | Immunogen: A synthesized peptide Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus Similarity: Pig (100%), Bovine (91%), Horse (100%), Sheep (91%), Rabbit (100%), Dog (100%), Xenopus (100%) |
Other Names | [AW610835; FLJ23467; Inflammation factor 20; Inflammation factor protein 20; TIPE2; TNF alpha-induced protein 8-like protein 2; TNFAIP8-like protein 2; TNFAIP8L2; TP8L2_HUMAN; Tumor necrosis factor alpha induced protein 8 like 2; Tumor necrosis factor alpha-induced protein 8-like protein 2] |
Gene, Accession # | [TNFAIP8L2], Gene ID: 79626, NCBI: NP_078851.2, UniProt: Q6P589 |
Catalog # | MBS9604787 |
Price | $240, $280 |
Order / More Info | TNFAIP8L2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |