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Antigenic Specificity | ESR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Estrogen receptor alpha (ERalpha), a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD) (1). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ERalpha regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery (2). Phosphorylation provides an important mechanism to regulate ERalpha activity (3,4). ERalpha is phosphorylated on multiple sites (5). Ser104, 106, 118 and 167 are located in the amino-terminal transcription activation function domain AF-1, and phosphorylation of these serines plays an important role in regulating ERalpha activity. Ser118 may be the subs |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [Estrogen Receptor alpha: Estrogen Receptor a; ESR1; DKFZp686N23123; ER; ESR; ESRA; Era; NR3A1; Estrogen Receptor alpha], [ESR1; ESR1; ER; ESR; Era; ESRA; ESTRR; NR3A1; ESR; NR3A1; ER] |
Gene, Accession # | [ESR1], Gene ID: 2099, NCBI: P03372.2, UniProt: P03372 |
Catalog # | MBS126560 |
Price | $235, $350 |
Order / More Info | ESR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |