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Antigenic Specificity | MAP3K13 (LZK) (C-term) |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Purified His-tagged MAP3K13 protein fragment was used to produced this monoclonal antibody. Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B. |
Immunogen | n/a |
Other Names | [Mitogen-activated protein kinase kinase kinase 13; Leucine zipper-bearing kinase; Mixed lineage kinase; MLK; MAP3K13] |
Gene, Accession # | [MAP3K13], Gene ID: 9175, NCBI: NP_001229243.1, UniProt: O43283 |
Catalog # | MBS9231365 |
Price | $165, $370 |
Order / More Info | MAP3K13 (LZK) (C-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Ikeda A., et al. J. Biochem. 130:773-781(2001). Masaki M., et al. Eur. J. Biochem. 270:76-83(2003). Greenman C., et al. Nature 446:153-158(2007). Sakuma H., et al. J. Biol. Chem. 272:28622-28629(1997). Ota T., et al. Nat. Genet. 36:40-45(2004). |