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Antigenic Specificity | Midkine |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total Midkine polyclonal antibody. Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity.Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development |
Immunogen | Immunogen: Recombinant Human Midkine protein |
Other Names | [Amphiregulin-associated protein; Midgestation and kidney protein; Neurite outgrowth-promoting factor 2; Neurite outgrowth-promoting protein; MDK; MK1; NEGF2] |
Gene, Accession # | Gene ID: 4192, NCBI: NP_001012333.1, UniProt: P21741 |
Catalog # | MBS9416241 |
Price | $320 |
Order / More Info | Midkine Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |