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Antigenic Specificity | CACNA1A (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB); ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CACNA1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 898-932 amino acids from the Central region of human CACNA1A. Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents. P/Q-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by the funnel toxin (Ftx) and by the omega-agatoxin- IVA (omega-Aga-IVA). They are however insensitive to dihydropyridines (DH |
Immunogen | n/a |
Other Names | [Purified Rabbit (Pab); Voltage-dependent P/Q-type calcium channel subunit alpha-1A; Brain calcium channel I; BI; Calcium channel; L type; alpha-1 polypeptide isoform 4; Voltage-gated calcium channel subunit alpha Cav21; CACNA1A; CACH4; CACN3; CACNL1A4] |
Gene, Accession # | [CACNA1A], Gene ID: 773, NCBI: NP_000059.3, UniProt: O00555 |
Catalog # | MBS9216411 |
Price | $165, $370 |
Order / More Info | CACNA1A (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Hans M.,et al.Biophys. J. 76:1384-1400(1999).Ophoff R.A.,et al.Cell 87:543-552(1996).Zhuchenko O.,et al.Nat. Genet. 15:62-69(1997).Toru S.,et al.J. Biol. Chem. 275:10893-10898(2000).Grimwood J.,et al.Nature 428:529-535(2004). |