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Antigenic Specificity | MFN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MFN1 antibody is human, mouse and rat reactive. MFN1 antibody is predicted to not cross-react with MFN2. Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes (1,2). MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development (3). When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondr |
Immunogen | Immunogen: MFN1 antibody was raised against a 17 amino acid peptide near the amino terminus of human MFN1. Buffer: MFN1 antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [MFN1; hfzo1; hfzo2; Mitofusin-1; Fzo homolog; mitofusin 1], [MFN1; MFN1; hfzo1; hfzo2] |
Gene, Accession # | [MFN1], Gene ID: 55669, NCBI: NP_284941, UniProt: Q8IWA4 |
Catalog # | MBS153700 |
Price | $375 |
Order / More Info | MFN1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |