MFN1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMFN1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
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DescriptionSpecificity: MFN1 antibody is human, mouse and rat reactive. MFN1 antibody is predicted to not cross-react with MFN2. Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes (1,2). MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development (3). When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondr
ImmunogenImmunogen: MFN1 antibody was raised against a 17 amino acid peptide near the amino terminus of human MFN1. Buffer: MFN1 antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[MFN1; hfzo1; hfzo2; Mitofusin-1; Fzo homolog; mitofusin 1], [MFN1; MFN1; hfzo1; hfzo2]
Gene, Accession #[MFN1], Gene ID: 55669, NCBI: NP_284941, UniProt: Q8IWA4
Catalog #MBS153700
Price$375
Order / More InfoMFN1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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