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Antigenic Specificity | LMNA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using LMNA antibody. Immunohistochemical staining of paraffin-embedded human breast tumor, showing staining of the nuclear envelope, using LMNA Antibody. Immunofluorescence analysis of HeLa cell using LMNA antibody. Blue: DAPI for nuclear staining. Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control, DNA replication, and chromatin organization (1-3). Lamin A/C is cleaved by caspase-6 and serves as a marker for caspase-6 activation. During apoptosis, lamin A/C is specifically cleaved into a large (41-50 kDa) and a small (28 kDa) fragment (3, 4). The cleavage of lamins results in nuclear disreg |
Immunogen | Immunogen: Recombinant protein of human LMNA |
Other Names | n/a |
Gene, Accession # | [LMNA] |
Catalog # | MBS419408 |
Price | $385 |
Order / More Info | LMNA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |