Lipin 1 (LPIN1), Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLipin 1 (LPIN1),
Clonepolyclonal
Host Speciesn/a
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatunconjugated
Size0.1 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC), Western Blot (WB)
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DescriptionThe Lipin family of nuclear proteins contains three members: Lipin-1, Lipin-2 and Lipin-3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain. LPIN1 (Lipin-1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC-1 target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPAR. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insuli
ImmunogenImmunogen: A synthetic peptide to an internal region (within residues 300-400) of the human LPIN1 protein. [Swiss-Prot# Q14693].
Other Names[phosphatidate phosphatase LPIN1 isoform 2; Phosphatidate phosphatase LPIN1; phosphatidate phosphatase LPIN1; lipin 1; Lipin-1], [LPIN1; LPIN1; PAP1; KIAA0188]
Gene, Accession #[LPIN1], Gene ID: 23175, NCBI: NP_001248356.1
Catalog #MBS555111
Price$430
Order / More InfoLipin 1 (LPIN1), Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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