CD46 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD46
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionActs as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity.
ImmunogenImmunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-320 of human CD46 (NP 722548.1).
Other Names[MCP; TLX; AHUS2; MIC10; TRA2.10]
Gene, Accession #[CD46], Gene ID: 4179, NCBI: P15529.3, UniProt: P15529
Catalog #MBS8544509
Price$280
Order / More InfoCD46 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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