Edit |   |
---|---|
Antigenic Specificity | eIF5A2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: eIF5A2 antibody detects endogenous levels of total eIF5A2. Function: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity).Post-translational Modifications: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue |
Immunogen | Immunogen: A synthesized peptide derived from human eIF5A2 Subcellular Location: Cytoplasm. Nucleus. Endoplasmic Reticulum Membrane. Nucleus > Nuclear Pore Complex. Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions. Tissue Specificity: Expressed in ovarian and colorectal cancer cell lines (at protein level). Highly expressed in tes |
Other Names | [9630038B20; eIF 5A 2; eIF 5A2; eIF-4D; eIF-5A-2; eIF-5A2; EIF5A 2; EIF5A2; eIF5AII; Eukaryotic initiation factor 5A isoform 2; Eukaryotic translation initiation factor 5A-2; Eukaryotic translation initiation factor 5A2; IF5A2_HUMAN] |
Gene, Accession # | [eIF5A2], Gene ID: 56648, NCBI: NP_065123.1, UniProt: Q9GZV4 |
Catalog # | MBS9608855 |
Price | $240, $280 |
Order / More Info | eIF5A2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |