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Antigenic Specificity | RAB38 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RAB38 antibody detects endogenous levels of total RAB38. Function: May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1. Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which probably is implicating vesicle-trafficking, includes cooperation with ANKRD27 and VAMP7 (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis (PubMed:21255211). Plays an important role in the control of melanin production and melanosome biogenesis (PubMed:23084991). In concert with RAB32, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarit |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Plasma Membrane Tissue Specificity: Expressed in melanocytes. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (91%), Bovine (91%), Horse (91%), Sheep (91%), Rabbit (100%), Dog (91%), Chicken (82%), Xenopus (91%) |
Other Names | [Antigen NY MEL 1; Melanoma antigen NY MEL 1; Melanoma antigen NY-MEL-1; NY MEL 1; RAB 38; Rab related GTP binding protein; Rab38; RAB38 member RAS oncogene family; RAB38_HUMAN; Ras related protein Rab 38; Ras-related protein Rab-38; rrGTPbp] |
Gene, Accession # | [RAB38], Gene ID: 23682, NCBI: NP_071732.1, UniProt: P57729 |
Catalog # | MBS9605858 |
Price | $240, $280 |
Order / More Info | RAB38 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |