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Antigenic Specificity | Toll-like receptor 11 (TLR11) (IN) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). TLR11 is one of three mouse TLRs that lack a human ortholog (6). It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system (7). |
Immunogen | Immunogen: Rabbit polyclonal TLR11 antibody was raised against a peptide corresponding to 16 amino acids near the middle of mouse TLR11. |
Other Names | [toll-like receptor 11; Toll-like receptor 11; toll-like receptor 11; toll-like receptor 11], [Tlr11; Tlr11; Gm287; Gm287] |
Gene, Accession # | [TLR11], Gene ID: 239081, NCBI: NP_991388.2, UniProt: Q6R5P0 |
Catalog # | MBS395936 |
Price | $405 |
Order / More Info | Toll-like receptor 11 (TLR11) (IN) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |