PKC iota, NT Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPKC iota, NT
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatammonium sulfate precipitate
Size0.2 mL
Concentration1.41mg/ml
ApplicationsELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionRecognizes human PKC. PKC iota belongs to the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehydes-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosi
ImmunogenImmunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 176-207 in the N-terminal region of human PKC iota, UniProt Accession #P41743.
Other NamesPKC iota, NT (Protein Kinase C iota Type, Atypical Protein Kinase C-lambda/iota, PRKC-lambda/iota, aPKC-lambda/iota, nPKC-iota, PRKCI, DXS1179E)
Gene, Accession #Gene ID: 5584, NCBI: NP_002731.4, UniProt: P41743
Catalog #MBS624797
Price$610
Order / More InfoPKC iota, NT Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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