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Antigenic Specificity | ITGAL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using ITGAL antibody. ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Immunogen: Recombinant Protein of human ITGAL |
Other Names | [integrin alpha-L isoform b; Integrin alpha-L; integrin alpha-L; integrin subunit alpha L; CD11 antigen-like family member A; Leukocyte adhesion glycoprotein LFA-1 alpha chain; LFA-1A; Leukocyte function-associated molecule 1 alpha chain; CD_antigen: CD11a], [ITGAL; ITGAL; CD11A; LFA-1; LFA1A; CD11A; LFA-1A] |
Gene, Accession # | [ITGAL], Gene ID: 3683, NCBI: NP_001107852.1, UniProt: P20701 |
Catalog # | MBS419746 |
Price | $385 |
Order / More Info | ITGAL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |