VGLUT1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityVGLUT1
Clone[S28-9]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
Formatunconjugated
Size0.1 mg
Concentration1mg/mL
ApplicationsImmunohistochemistry (IHC), Western Blot (WB)
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DescriptionBackground Info: Detects ~52kDa. No cross-reactivity against VGLUT2. Scientific Background: VGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesicles from the brain, exhibiting a conductance for chloride that is blocked by glutamate (1). Vesicular glutamate transport has a substantially lower apparent affinity than the plasma membrane excitatory amino acid transporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM, in the same range as transport by synaptic vesicles. Finally, plasma membrane glutamate transporters recognize both aspartate and glutamate as substrates, whereas VGLUT1 does not recognize aspartate (2).
Immunogenn/a
Other Names[BNPI; SLC17A1; SLC17A1/VGLUT1; Solute Carrier family 17 member 7; Vesicular glutamate transporter 1; VGLUT 1; Brain-specific Na(+)-dependent inorganic phosphate cotransporter], [Slc17a7; Slc17a7; BNPI; Vglut1; Bnpi; Vglut1; VGluT1]
Gene, Accession #Gene ID: 116638, NCBI: NP_446311.1, UniProt: Q62634
Catalog #MBS800216
Price$390
Order / More InfoVGLUT1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Wojcik S.M., et al. (2004) PNAS. 101(18): 7158-7163. 2. Shigeri Y., Seal R.P., Shimamoto K. (2004) Brain Res Rev. 45(3): 250-265.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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