CCR4 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-CCR4 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | CCR4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CCR4 antibody detects endogenous levels of total CCR4. Function: High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.Post-translational Modifications: In natural killer cells, CCL22 binding induces phosphorylation on yet undefined Ser/Thr residues, most probably by beta-adrenergic receptor kinases 1 and 2.Similarity: Belongs to the G-protein coupled receptor |
| Immunogen | Immunogen: A synthesized peptide derived from human CCR4 Subcellular Location: Cell Membrane Tissue Specificity: Predominantly expressed in the thymus, in peripheral blood leukocytes, including T-cells, mostly CD4 cells, and basophils, and in platelets; at lower levels, in the spleen and in monocytes. Detected also in macrophages, IL-2-activated natural killer cells and skin-homing memory T-cells, mostly the ones expressing the cutaneous lymphocyte antigen (CLA). Expressed in brain microvascular |
| Other Names | [C C chemokine receptor type 4; C C CKR 4; C-C chemokine receptor type 4; C-C CKR-4; CC CKR 4; CC-CKR-4; CCR 4; CCR-4; CCR4; CCR4_HUMAN; CD194; Chemokine (CC motif) receptor 4; chemokine C C motif receptor 4; ChemR13; CKR4; CMKBR 4; CMKBR4; HGCN 14099; K5 5; K5-5; MGC88293] |
| Gene, Accession # | [CCR4], Gene ID: 1233, NCBI: NP_005499.1, UniProt: P51679 |
| Catalog # | MBS9603064 |
| Price | $240, $280 |
| Order / More Info | CCR4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies