NRG4 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NRG4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: NRG4 antibody detects endogenous levels of total NRG4. Description: The neuregulins, including NRG4, activate type-1 growth factor receptors (see EGFR; MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al., 1999 [PubMed 10348342]).Function: Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors (By similarity).Subunit Structure: Interacts with ERBB4.Post-translational Modifications: Proteolytic cleavage close to the plasma membrane on the external face leads to the release |
| Immunogen | Immunogen: A synthesized peptide derived from human NRG4 Subcellular Location: Secreted and Cell Membrane. Does not seem to be active. Predicted Cross Reactivity: Pig, Horse, Sheep Similarity: Pig (100%), Horse (89%), Sheep (88%) |
| Other Names | [DKFZp779N0541; DKFZp779N1944; Heregulin 4; HRG4; Neuregulin 4; Neuregulin-4; NRG-4; NRG4; NRG4_HUMAN; pro-neuregulin-4, membrane-bound isoform; Pro-NRG4] |
| Gene, Accession # | [NRG4], Gene ID: 145957, NCBI: NP_612640.1, UniProt: Q8WWG1 |
| Catalog # | MBS9607699 |
| Price | $240, $280 |
| Order / More Info | NRG4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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