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Antigenic Specificity | ACTIN1 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | 0.02 mL, 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Thre |
Immunogen | Source Note: This monoclonal antibody is produced by immunizing mice with a sythetic peptide(KLH coupled)corresponding to amino-terminal residues of human ACTN1 |
Other Names | [alpha Actinin Mouse mAb; Actinin; actinin 1 smooth muscle; actinin, alpha 1; alpha 1; alpha actinin 1a; alpha-actinin 1; Alpha-actinin cytoskeletal isoform; Alpha-actinin-1; F-actin cross-linking protein; FLJ40884; non-muscle alpha-actinin 1; Non-muscle alpha-actinin-1; 3110023F10Rik; ACTN1; Actn1a; BDPLT15; BOS_11045], [ACTN1] |
Gene, Accession # | [ACTIN1], Gene ID: 87, NCBI: NP_001093.1, UniProt: P12814 |
Catalog # | MBS435099 |
Price | $225, $350, $565 |
Order / More Info | ACTIN1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |