ZC3H12A Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ZC3H12A |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ZC3H12A Antibody: ZC3H12A, also known as MCPIP, is an essential member of a family of novel CCCH-zinc finger proteins that regulate macrophage activation and may be involved in host immunity and inflammatory diseases. ZC3H12A has RNase activity that prevents some immune disorders by directly affecting the mRNA stability of interleukins such as IL-6 and IL12p40. Mice lacking the ZC3H12A gene suffered from severe anemia, and most dies within 12 weeks. Overexpression of ZC3H12A causes ER stress and induces a number of genes involved in apoptosis and autophagy, including JNK, PUMA, and beclin-1 in cardiac myoblasts, leading to cell death. ZC3H12A can also induce adipogenesis in 3T3-L1 pre-adipocytes in the absence of PPAPgamma, demonstrating th |
| Immunogen | Immunogen: ZC3H12A antibody was raised against a 17 amino acid synthetic peptide near the center of human ZC3H12A. Buffer: ZC3H12A Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [ZC3H12A; MCPIP; MCPIP1; dJ423B22.1; MCPIP; Ribonuclease ZC3H12A; MCP-induced protein 1; zinc finger CCCH-type containing 12A], [ZC3H12A; ZC3H12A; MCPIP; MCPIP1; dJ423B22.1] |
| Gene, Accession # | [ZC3H12A], Gene ID: 80149, NCBI: NP_079355, UniProt: Q5D1E8 |
| Catalog # | MBS150988 |
| Price | $375 |
| Order / More Info | ZC3H12A Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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