Edit |   |
---|---|
Antigenic Specificity | Mouse CD94 |
Clone | [18d3] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a kappa |
Format | unconjugated |
Size | 0.5 mg |
Concentration | n/a |
Applications | Flow Cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Mouse CD94 receptor subunit, Mr 70 kDa. The monoclonal antibody 18D3 reacts with the mouse CD94 receptor subunit, a 70kDa type II transmembrane glycoprotein. CD94 is expressed on the surface of NK cells, NK T cells and some memory phenotype CD8+ cells.2 When CD94 is paired with NKG2A, C, or E subunit, it binds the nonclassical MHC class Ib molecule Qa-1b and results in a CD94high population by flow cytometry.1, 2 Approximately half of NK cells do not express NKG2A, C or E; these cells express CD94 on the surface in a form that does not bind Qa-1b and is believed to be nonfunctional, producing a CD94low population by flow cytometry.1, 2 CD94 is thought to play a role in the adhesion and activation of the NK cell lineage. |
Immunogen | Immunogen: CHO cells transfected with the B6 allele of CD94 |
Other Names | [Rat Mouse CD94 - Purified, Unlabeled; Rat Mouse CD94], [KLRD1; KLRD1; CD94; CD94] |
Gene, Accession # | Gene ID: 3824, UniProt: Q13241 |
Catalog # | MBS673581 |
Price | $260 |
Order / More Info | Mouse CD94 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Vance, R.E., A.M. Jamieson, and D.H. Raulet. 1999. J. Exp. Med. 190:1801.2. Liu, S., and D.H. Raulet. Personal communication. |