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Antigenic Specificity | ATG4B - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ATG4B |
Other Names | [cysteine protease ATG4B isoform a; Cysteine protease ATG4B; cysteine protease ATG4B; autophagy related 4B cysteine peptidase; AUT-like 1 cysteine endopeptidase; Autophagin-1; Autophagy-related cysteine endopeptidase 1; Autophagy-related protein 4 homolog B] |
Gene, Accession # | [ATG4B], Gene ID: 23192, NCBI: NP_037457.3, UniProt: Q9Y4P1 |
Catalog # | MBS3224126 |
Price | $335 |
Order / More Info | ATG4B - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |