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Antigenic Specificity | TPBG |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TPBG antibody detects endogenous levels of total TPBG. Function: May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization.Post-translational Modifications: Highly glycosylated.Similarity: The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. |
Immunogen | Immunogen: A synthesized peptide derived from human TPBG Subcellular Location: Plasma Membrane Tissue Specificity: Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma. Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Sheep (100%), |
Other Names | [5T4; 5T4 oncofetal antigen; 5T4 oncofetal trophoblast glycoprotein; 5T4 oncotrophoblast glycoprotein; 5T4AG; AW495680; M6P1; TPBG; TPBG_HUMAN; Trophoblast glycoprotein] |
Gene, Accession # | [TPBG], Gene ID: 7162, NCBI: NP_001159864.1, UniProt: Q13641 |
Catalog # | MBS9608767 |
Price | $240, $280 |
Order / More Info | TPBG Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |