Pcsk1n - N-terminal region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Pcsk1n - N-terminal region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | cow, dog, guinea pig, human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This is a rabbit polyclonal antibody against Pcsk1n. It was validated on Western BlotTarget Description: Pcsk1n may function in the control of the neuroendocrine secretory pathway. It is proposed to be a specific endogenous inhibitor of PCSK1. ProSAAS and Big PEN-LEN, both containing the C-terminal inhibitory domain, but not the processed peptides reduce PCSK1 activity in the endoplasmic reticulum and Golgi. It reduces the activity of the 87 kDa form but not the autocatalytically derived 65 kDa form of PCSK1. Subsequent processing of proSAAS may eliminate the inhibition. Slows down convertase-mediated processing of proopiomelanocortin and proenkephalin. Pcsk1n may control the intracellular timing of PCSK1 rather than its total level |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Pcsk1n |
| Other Names | [proSAAS; ProSAAS; proSAAS; proprotein convertase subtilisin/kexin type 1 inhibitor; Proprotein convertase subtilisin/kexin type 1 inhibitor; Proprotein convertase 1 inhibitor; pro-SAASCleaved into the following 8 chains:KEP; Big SAAS; b-SAAS; Little SAAS; l-SAAS; Big PEN-LEN; b-PEN-LENAlternative name(s):SAAS CT(1-49)] |
| Gene, Accession # | [PCSK1N], Gene ID: 246333, NCBI: NP_062152, UniProt: Q9QXU9 |
| Catalog # | MBS3214232 |
| Price | $335 |
| Order / More Info | Pcsk1n - N-terminal region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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