Edit |   |
---|---|
Antigenic Specificity | GSK3beta (Phospho-Ser9) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous human, mouse, and rat GSK3 beta only when phosphorylated at serine 9. GSK3beta participates in the Wnt signaling pathway and is implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. GSK3beta phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. It also phosphorylates CTNNB1/beta-catenin and MUC1 in breast cancer cells and decreases the interaction of MUC1 with CTNNB1/beta-catenin. |
Immunogen | Antigen: Peptide sequence that includes phosphorylation site of serine 9 (T-T-S(p)-F-A) derived from Human GSK3beta and conjugated to KLH. |
Other Names | [glycogen synthase kinase-3 beta isoform 2; Glycogen synthase kinase-3 beta; glycogen synthase kinase-3 beta; glycogen synthase kinase 3 beta; Serine/threonine-protein kinase GSK3B (EC:2.7.11.1)], [GSK3B; GSK3B; GSK-3 beta] |
Gene, Accession # | [GSK3beta], Gene ID: 2932, NCBI: NP_001139628.1, UniProt: P49841 |
Catalog # | MBS191014 |
Price | $340 |
Order / More Info | GSK3beta (Phospho-Ser9) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |