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Antigenic Specificity | SLC27A5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total SLC27A5 protein. Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol.Steinberg S.J., Mol. Genet. Metab. 68:32-42(1999).Steinberg S.J., J. Biol. Chem. 275:15605-15608(2000).Mihalik S.J., J. Biol. Chem. 277:24771-24779(2002). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human SLC27A5. |
Other Names | [EC 6.2.1.7; FACVL3; FATP5; MGC143799; S27A5] |
Gene, Accession # | [SLC27A5], Gene ID: 10998, NCBI: NP_036386.1, UniProt: Q9Y2P5 |
Catalog # | MBS9403347 |
Price | $200, $255 |
Order / More Info | SLC27A5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |