SLC27A5 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySLC27A5
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThe antibody detects endogenous levels of total SLC27A5 protein. Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol.Steinberg S.J., Mol. Genet. Metab. 68:32-42(1999).Steinberg S.J., J. Biol. Chem. 275:15605-15608(2000).Mihalik S.J., J. Biol. Chem. 277:24771-24779(2002).
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human SLC27A5.
Other Names[EC 6.2.1.7; FACVL3; FATP5; MGC143799; S27A5]
Gene, Accession #[SLC27A5], Gene ID: 10998, NCBI: NP_036386.1, UniProt: Q9Y2P5
Catalog #MBS9403347
Price$200, $255
Order / More InfoSLC27A5 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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