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Antigenic Specificity | KDM1B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: KDM1B antibody is human, mouse and rat reactive. At least two isoforms of KDM1B are known to exist; this KDM1B antibody will detect both isoforms. Flavin-dependent histone demethylases regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (reviewed in 1). KDM1B is a recently identified histone H3K4 demethylase that is required to establish maternal genomic imprints; targeted disruption of the KDM1B gene in mice led to lethality in their embryos, suggesting demethylation of H3K4 is critical for establishing the DNA methylation imprints (2). KDM1B has also been shown to play a role in the transcription elongation in several genes (3). |
Immunogen | Immunogen: KDM1B antibody was raised against a 17 amino acid peptide near the amino terminus of human KDM1B. Buffer: KDM1B antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [KDM1B; AOF1; LSD2; C6orf193; bA204B7.3; dJ298J15.2; AOF1; Lysine-specific histone demethylase 1B; Flavin-containing amine oxidase domain-containing protein 1; lysine (K)-specific demethylase 1B], [KDM1B; KDM1B; AOF1; LSD2; C6orf193; bA204B7.3; dJ298J15.2; AOF1; C6orf193; LSD2] |
Gene, Accession # | [KDM1B], Gene ID: 221656, NCBI: NP_694587, UniProt: Q8NB78 |
Catalog # | MBS153627 |
Price | $375 |
Order / More Info | KDM1B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |