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Antigenic Specificity | CD11b |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. |
Immunogen | Immunogen: A synthesized peptide derived from human CD11b. Subcellular Localization: Membrane; Single-pass type I membrane protein. Tissue Specificity: Predominantly expressed in monocytes and granulocytes. |
Other Names | [Integrin alpha-M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD11b; ITGAM; CD11B; CR3A], [ITGAM] |
Gene, Accession # | [CD11b], Gene ID: 3684, NCBI: NP_000623.2, UniProt: P11215 |
Catalog # | MBS179139 |
Price | $160, $340, $340 |
Order / More Info | CD11b Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |