CD8A (Cytotoxic-&Suppressor T-Cell Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD8A (Cytotoxic-&Suppressor T-Cell Marker) |
| Clone | [rC8/468] |
| Host Species | Mouse |
| Reactive Species | human. |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4.It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 |
| Immunogen | Immunogen: Recombinant full-length human CD8 protein Cellular Localization: Cell Surface |
| Other Names | [CD8 antigen; alpha polypeptide (p32); T8/Leu-2 T-lymphocyte differentiation antigen; Ly3; LYT3; MAL; T-cell surface glycoprotein CD8 alpha chain] |
| Gene, Accession # | [CD8A], Gene ID: 925, NCBI: NP_001139345.1, UniProt: P01732 |
| Catalog # | MBS4380312 |
| Price | $190, $340, $340 |
| Order / More Info | CD8A (Cytotoxic-&Suppressor T-Cell Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Mason DY, et. al. Journal of Clinical Pathology, 1992, 45(12):1084-8. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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