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Antigenic Specificity | RAP1A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rap1 and Rap2 belong to the Ras subfamily of small GTPases and are activated by a wide variety of stimuli through integrins, receptor tyrosine kinases (RTKs), G-protein coupled receptors (GPCR), death domain associated receptors (DD-R) and ion channels (1,2). Like other small GTPases, Rap activity is stimulated by guanine nucleotide exchange factors (GEF) and inactivated by GTPase activating proteins (GAP). A wide variety of Rap GEFs have been identified: C3G connects Rap1 with RTKs through adaptor proteins such as Crk, Epacs (or cAMP-GEFs) transmit signals from cAMP, and CD-GEFs (or CalDAG-GEFs) convey signals from either or both Ca2+ and DAG (1). Rap1 primarily regulates multiple integrin-dependent processes such as morphogenesis, cell-ce |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [RAP1A; KREV-1; KREV1; RAP1; SMGP21], [RAP1A; RAP1A; RAP1; C21KG; G-22K; KREV1; KREV-1; SMGP21; KREV1] |
Gene, Accession # | [RAP1A], Gene ID: 5906, NCBI: P62834.1, UniProt: P62834 |
Catalog # | MBS126616 |
Price | $200, $275, $430 |
Order / More Info | RAP1A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |