Myosin Light Chain 2, phosphorylated (Ser19) (MLC2, Myosin Regulatory Light Chain, MRLC, RLC, LC20) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Myosin Light Chain 2, phosphorylated (Ser19) (MLC2, Myosin Regulatory Light Chain, MRLC, RLC, LC20) antibody, protein, ELISA kits.
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| Antigenic Specificity | Myosin Light Chain 2, phosphorylated (Ser19) (MLC2, Myosin Regulatory Light Chain, MRLC, RLC, LC20) |
| Clone | [4i15] |
| Host Species | Mouse |
| Reactive Species | bovine, mouse, porcine, rat. does not crossreact with the cardiac isoform of Myosin Light Chain 2. |
| Isotype | IgG1 |
| Format | ascites |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC). Other applications not tested. |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes endogenous levels of human Myosin Light Chain 2 (smooth muscle) at ~18kD only when phosphorylated at serine 19. Myosin is composed of six polypeptide chains: two identical heavy chains and two pairs of light chains. Myosin light chain 2 (MLC2), also known as myosin regulatory light chain (MRLC or RLC, LC20), has many isoforms depending on its distribution. In smooth muscle, MLC2 is phosphorylated at Thr18 and Ser19 by myosin light chain kinase (MLCK) in a Ca2+/calmodulindependent manner (1). This phosphorylation is correlated with myosin ATPase activity and smooth muscle contraction (2). ROCK also phosphorylates Ser19 of smooth muscle MLC2, which regulates the assembly of stress fibers (3). Phosphorylation of smooth muscle MLC2 a |
| Immunogen | Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Ser19 of human Myosine Light Chain 2 (smooth muscle). |
| Other Names | [-Myosin Light Chain 2, phosphorylated (Ser19) (MLC2, Myosin Regulatory Light Chain, MRLC, RLC, LC20)], [MYL2; MYL2; MLC2; CMH10; DKFZp779C0562] |
| Gene, Accession # | Gene ID: 4633, NCBI: NP_000423.2, UniProt: P10916 |
| Catalog # | MBS609646 |
| Price | $595 |
| Order / More Info | Myosin Light Chain 2, phosphorylated (Ser19) (MLC2, Myosin Regulatory Light Chain, MRLC, RLC, LC20) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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