Phospho-MAPKAPK-2 (Thr334) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-MAPKAPK-2 (Thr334)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshumanpredicted: mouse, rabbit
Isotypen/a
Formatunconjugated
Size0.05 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis Phospho-MAPKAPK-2 (Thr334) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 308-341 amino acids from human Phospho-MAPKAPK-2. Stress-activated serine/threonine-protein kinase involved in cytokines production, endocytosis, reorganization of the cytoskeleton, cell migration, cell cycle control, chromatin remodeling, DNA damage response and transcriptional regulation. Following stress, it is phosphorylated and activated by MAP kinase p38-alpha/MAPK14, leading to phosphorylation of substrates. Phosphorylates serine in the peptide sequence, Hyd-X-R-X (2)-S, where Hyd is a large hydrophobic residue. Phosphorylates ALOX5, CDC25B, CDC25C, ELAVL1, HNRNPA0, HSF1, HSP27/HSPB1, KRT18, KRT20, LIMK1, LSP1
Immunogenn/a
Other Names[MAP kinase-activated protein kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2; MAPKAP-K2; MAPKAPK-2; MK-2; MK2; 2.7.11.1; MAPKAPK2]
Gene, Accession #[MAPKAPK-2], Gene ID: 9261, NCBI: NP_004750.1, UniProt: P49137
Catalog #MBS9231102
Price$165, $370
Order / More InfoPhospho-MAPKAPK-2 (Thr334) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesZu Y.-L.,et al.Biochem. Biophys. Res. Commun. 200:1118-1124 (1994). Gregory S.G.,et al.Nature 441:315-321 (2006). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Stokoe D.,et al.Biochem. J. 296:843-849 (1993). Jakob U.,et al.J. Biol. Chem. 268:1517-1520 (1993).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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