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Antigenic Specificity | Phospho-MAPKAPK-2 (Thr334) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | humanpredicted: mouse, rabbit |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Phospho-MAPKAPK-2 (Thr334) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 308-341 amino acids from human Phospho-MAPKAPK-2. Stress-activated serine/threonine-protein kinase involved in cytokines production, endocytosis, reorganization of the cytoskeleton, cell migration, cell cycle control, chromatin remodeling, DNA damage response and transcriptional regulation. Following stress, it is phosphorylated and activated by MAP kinase p38-alpha/MAPK14, leading to phosphorylation of substrates. Phosphorylates serine in the peptide sequence, Hyd-X-R-X (2)-S, where Hyd is a large hydrophobic residue. Phosphorylates ALOX5, CDC25B, CDC25C, ELAVL1, HNRNPA0, HSF1, HSP27/HSPB1, KRT18, KRT20, LIMK1, LSP1 |
Immunogen | n/a |
Other Names | [MAP kinase-activated protein kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2; MAPKAP-K2; MAPKAPK-2; MK-2; MK2; 2.7.11.1; MAPKAPK2] |
Gene, Accession # | [MAPKAPK-2], Gene ID: 9261, NCBI: NP_004750.1, UniProt: P49137 |
Catalog # | MBS9231102 |
Price | $165, $370 |
Order / More Info | Phospho-MAPKAPK-2 (Thr334) Antibody from MYBIOSOURCE INC. |
Product Specific References | Zu Y.-L.,et al.Biochem. Biophys. Res. Commun. 200:1118-1124 (1994). Gregory S.G.,et al.Nature 441:315-321 (2006). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Stokoe D.,et al.Biochem. J. 296:843-849 (1993). Jakob U.,et al.J. Biol. Chem. 268:1517-1520 (1993). |