Amyloid precursor protein (APP) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAmyloid precursor protein (APP)
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a
FormatProtein A purified
Size0.05 mg
Concentration1ug/ul
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionAmyloid precursor protein (APP), with 32-amino acid protein (about 35 kDa), is part of a super-family of transmembrane and secreted proteins. It appears to have a number of roles, including regulation of haemostasis and mediation of neuroprotection. APP undergoes alternative splicing, resulting in several isoforms. Proteolytic cleavage of amyloid precursor protein leads to the formation of the 4 kDa amyloid beta/A4 protein, which is present in human platelets. APP is also involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer patients.
ImmunogenImmunogen: Ni-NTA purified truncated recombinant APP expressed in E Coli strain BL21 (DE3)
Other Namesn/a
Gene, Accession #[APP]
Catalog #MBS418364
Price$445
Order / More InfoAmyloid precursor protein (APP) Antibody from MYBIOSOURCE INC.
Product Specific References1.Yuzhi Chen, Wenyun Liu, Donna L, et al. J. Cell Biol., Oct 2003; 163: 27. 2.Robert Spoelgen, Christine A. F. von Arnim, et al. J. Neurosci., Jan 2006; 26: 418 - 428.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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