Phospho-CRK-Y221 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Phospho-CRK-Y221 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. |
| Immunogen | Immunogen: A synthetic phosphorylated peptide around Y221 of human CRK (NP 058431.2). |
| Other Names | [adapter molecule crk isoform b; Adapter molecule crk; adapter molecule crk; CRK proto-oncogene, adaptor protein; Proto-oncogene c-Crk; p38] |
| Gene, Accession # | [CRK], Gene ID: 1398, NCBI: NP_005197.3, UniProt: P46108 |
| Catalog # | MBS8574649 |
| Price | $280 |
| Order / More Info | Phospho-CRK-Y221 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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