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Antigenic Specificity | IL36 alpha/IL36A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA Capture (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for IL36 alpha detection. Tested with WB, IHC-P, ELISA (Cap) in Human; Mouse; Rat.Background: Interleukin-36 alpha also known as interleukin-1 family member 6 (IL1F6) is a protein that in humans is encoded by the IL36A gene. The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients. |
Immunogen | Immunogen: E Coli-derived human IL36 alpha recombinant protein (Position: K6-D151). |
Other Names | [Interleukin-36 alpha; FIL1 epsilon; Interleukin-1 epsilon; IL-1 epsilon; Interleukin-1 family member 6; IL-1F6; IL36A; FIL1E; IL1E; IL1F6; Interleukin 36, alpha] |
Gene, Accession # | [IL36A], Gene ID: 27179, NCBI: NP_055255.1, UniProt: Q9UHA7 |
Catalog # | MBS1751518 |
Price | $315 |
Order / More Info | IL36 alpha/IL36A Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Smith DE, Renshaw BR, Ketchem RR, Kubin M, Garka KE, Sims JE (Feb 2000). Four new members expand the interleukin-1 superfamily. J Biol Chem. 275 (2): 1169-75. |