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Antigenic Specificity | GAPDH |
Clone | [AT8G4] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, k |
Format | Protein G purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Multiple roles for glyceraldehyde-3-phosphate dehydrogenase (GAPDH) have been recently appreciated. GAPDH is found in the particulate fractions, such as the nucleus, the mitochondria, and the small vesicular fractions. GAPDH gene expression is specifically increased during programmed neuronal cell death. When cells are exposed to various stressors, dynamic subcellular re-distribution of GAPDH occurs. GAPDH is also involved in various diseases, especially neurodegenerative disorders and cancers. As a membrane protein, GAPDH functions in endocytosis; in the cytoplasm, it is involved in the translational control of gene expression; in the nucleus, it functions in nuclear tRNA export, in DNA replication, and in DNA repair. |
Immunogen | Immunogen: Recombinant human GAPDH (1-335aa) purified from E Coli |
Other Names | [Glyceraldehyde-3-phosphate dehydrogenase; G3PD; GAPD; MGC88685; Glyceraldehyde-3-phosphate dehydrogenase; GAPDH; Glyceraldehyde-3-phosphate dehydrogenase 38 kDa BFA-dependent ADP-ribosylation substrate; Aging-associated gene 9 protein; BARS-38; cb609; EC 1.2.1.12; G3PDH; OCAS; p38 component; Glyceraldehyde 3 phosphate dehydrogenase; KNC-NDS6; MGC102544; MGC102546; MGC103190; MGC103191; MGC105239; MGC127711; OCT1 coactivator in S phase; 38-KD component; OTTHuMP00000174431; OTTHuMP00000174432; wu:fb33a10.], [GAPDH; GAPDH; G3PD; GAPD; HEL-S-162eP; GAPD; GAPDH] |
Gene, Accession # | [GAPDH], Gene ID: 2597, NCBI: NP_002037, UniProt: P04406 |
Catalog # | MBS200179 |
Price | $240, $315 |
Order / More Info | GAPDH Antibody from MYBIOSOURCE INC. |
Product Specific References | Chuang DM, et al. (2005) Annu Rev Pharmacol Toxicol, 45:269-90.; Mazzola JL, et al. (2002) Neurotoxicology, 23 (4-5):603-9.; Sirover MA. (1997) J Cell Biochem, 66 (2):133-40. |