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Antigenic Specificity | RUVBL1 |
Clone | [507CT2.2.2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.25 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Purified His-tagged RUVBL1 protein(Fragment) was used to produced this monoclonal antibody. Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome -DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and |
Immunogen | n/a |
Other Names | [RuvB-like 1; 49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP-interacting protein; 54 kDa erythrocyte cytosolic protein; ECP-54; INO80 complex subunit H; Nuclear matrix protein 238; NMP 238; Pontin 52; TIP49a; TIP60-associated protein 54-alpha; TAP54-alpha; RUVBL1; INO80H; NMP238; TIP49; TIP49A] |
Gene, Accession # | [RUVBL1], Gene ID: 8607, NCBI: NP_003698.1, UniProt: Q9Y265 |
Catalog # | MBS9200104 |
Price | $165, $370 |
Order / More Info | RUVBL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | Notaridou, M., et al. Int. J. Cancer (2010) In press : Niewiarowski, A., et al. Biochem. J. 429(1):113-125(2010) Izumi, N., et al. Sci Signal 3 (116), RA27 (2010) : Haurie, V., et al. Hepatology 50(6):1871-1883(2009) McKeegan, K.S., et al. Mol. Cell. Biol. 29(18):4971-4981(2009) |