RUVBL1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRUVBL1
Clone[507CT2.2.2]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.25
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: Purified His-tagged RUVBL1 protein(Fragment) was used to produced this monoclonal antibody. Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome -DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and
Immunogenn/a
Other Names[RuvB-like 1; 49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP-interacting protein; 54 kDa erythrocyte cytosolic protein; ECP-54; INO80 complex subunit H; Nuclear matrix protein 238; NMP 238; Pontin 52; TIP49a; TIP60-associated protein 54-alpha; TAP54-alpha; RUVBL1; INO80H; NMP238; TIP49; TIP49A]
Gene, Accession #[RUVBL1], Gene ID: 8607, NCBI: NP_003698.1, UniProt: Q9Y265
Catalog #MBS9200104
Price$165, $370
Order / More InfoRUVBL1 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesNotaridou, M., et al. Int. J. Cancer (2010) In press : Niewiarowski, A., et al. Biochem. J. 429(1):113-125(2010) Izumi, N., et al. Sci Signal 3 (116), RA27 (2010) : Haurie, V., et al. Hepatology 50(6):1871-1883(2009) McKeegan, K.S., et al. Mol. Cell. Biol. 29(18):4971-4981(2009)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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