Cystatin A Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Cystatin A |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Cystatin-A(CSTA) detection. Tested with WB, IHC-P in Human. Background: Cystatin A also called Stefin A is a protein that in humans is encoded by the CSTA gene. Cystatin A is a cysteine proteinase inhibitor that belongs to family 1 of the cystatin superpamily. This gene was assigned to human chromosome 3q21.1. This is an intracellular thiol proteinase inhibitor. Cystatin A plays an important role in desmosome-mediated cell-cell adhesion in the lower levels of the epidermis. Stefins have been proposed as prognostic and diagnostic tools for cancer. |
| Immunogen | Immunogen: E Coli-derived human Cystatin A recombinant protein (Position: E8-F98). Human Cystatin A shares 61.5% and 58.2% amino acid (aa) sequence identity with mouse and rat Cystatin A, respectively. Ig Type: Rabbit IgG |
| Other Names | [Cystatin-A; AREI; CSTA; CSTA protein; Cystatin A; Cystatin AS; Cystatin-A; Cystatin-AS; CystatinA; CYTA_HUMAN; Stefin A; Stefin A1; Stefin-A; StefinA; STF 1; STF1; STFA; cystatin A (stefin A)], [CSTA; CSTA; AREI; PSS4; STF1; STFA; STF1; STFA] |
| Gene, Accession # | Gene ID: 1475, NCBI: NP_005204.1, UniProt: P01040 |
| Catalog # | MBS178130 |
| Price | $315 |
| Order / More Info | Cystatin A Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Blaydon, D. C., Nitoiu, D., Eckl, K.-M., Cabral, R. M., Bland, P., Hausser, I., van Heel, D. A., Rajpopat, S., Fischer, J., Oji, V., Zvulunov, A., Traupe, H., Hennies, H. C., Kelsell, D. P. Mutations in CSTA, encoding cystatin A, underlie exfoliative ichthyosis and reveal a role for this protease inhibitor in cell-cell adhesion. Am. J. Hum. Genet. 89: 564-571, 2011. 2. Samuelsson, L., Stiller, C., Friberg, C., Nilsson, C., Inerot, A., Wahlstrom, J.Association analysis of cystatin A and zinc finger protein 148, two genes located at the psoriasis susceptibility locus PSORS5. J. Invest. Derm. 122: 1399-1400, 2004. 3. Vasilopoulos, Y., Walters, J., Cork, M. J., Duff, G. W., Sagoo, G. S., Tazi-Ahnini, R.Association analysis of the skin barrier gene cystatin A at the PSORS5 locus in psoriatic patients: evidence for interaction between PSORS1 and PSORS5.Europ. J. Hum. Genet. 16: 1002-1009, 2008. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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