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Antigenic Specificity | Human SAA |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Goats were immunized with highly purified recombinant human SAA. The resulting antiserum was passed over an antigen containing immunoabsorbant from which the anti-human SAA was immunoaffinity purified. Function: Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin- 1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate sign |
Immunogen | Procedure: Goats were immunized with highly purified recombinant Human SAA. Antiserum was collected and immunoaffinity purified off an antigen containing immunoabsorbant. Cellular Location: Cytoplasm. Late endosome. Nucleus. Endoplasmic reticulum. Lysosome. Cytoplasmic vesicle, autophagosome. Cytoplasm, P-body. Note=Sarcomere. In cardiac muscles localizes to the sarcomeric band. May also localize to the hepatocellular carcinoma. Colocalizes with TRIM13 in the perinuclear endoplasmic reticulum (B |
Other Names | [Affinity Purified Goat Human SAA; Human SAA (Serum Amyloid A)], [SAA1; SAA] |
Gene, Accession # | Gene ID: 678660, NCBI: NP_001035288.1 |
Catalog # | MBS560674 |
Price | $265 |
Order / More Info | Human SAA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |