IGF1R Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIGF1R
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous level of total IGF1R antibody. IGF1R, also named as CD221, belongs to the protein kinase superfamily, Tyr protein kinase family and Insulin receptor subfamily. IGF1R binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, IGF1R binds IGF1. The hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by I
ImmunogenImmunogen Type: Peptide Immunogen Description: N term -peptide of human IGF1R.
Other Names[IGF1R; CD221; IGFIR; IGFR; JTK13; MGC142170; MGC142172; MGC18216]
Gene, Accession #[IGF1R], Gene ID: 3480, NCBI: NP_000866.1, UniProt: P08069
Catalog #MBS9404671
Price$255
Order / More InfoIGF1R Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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