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Antigenic Specificity | Escherichia coli cAMP-activated global transcriptional regulator CRP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Escherichia coli |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | A global transcription regulator. Complexes with cyclic AMP (cAMP) which allosterically activates DNA binding (to consensus sequence 5'-AAATGTGATCTAGATCACATTT-3') to directly regulate the transcription of about 300 genes in about 200 operons and indirectly regulate the expression of about half the genome. There are 3 classes of CRP promoters; class I promoters have a single CRP-binding site upstream of the RNA polymerase (RNAP)-binding site, whereas in class II promoters the single CRP- and RNAP-binding site overlap, CRP making multiple contacts with RNAP. Class III promoters require multiple activator molecules, including at least one CRP dimer. It can act as an activator, repressor, coactivator or corepressor. Induces a severe bend in DNA |
Immunogen | Immunogen: Recombinant Escherichia coli cAMP-activated global transcriptional regulator CRP protein |
Other Names | [Catabolite activator protein; CAP; Catabolite gene activator; cAMP receptor protein; CRP; cAMP regulatory protein; crp; cap; csm; b3357; JW5702], [crp; crp; cap; csm; ECK3345; JW5702; cap; csm; CAP; CRP] |
Gene, Accession # | [CRP], Gene ID: 947867, NCBI: NP_417816.1, UniProt: P0ACJ8 |
Catalog # | MBS1488549 |
Price | $160, $235 |
Order / More Info | Escherichia coli cAMP-activated global transcriptional regulator CRP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |