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Antigenic Specificity | AGR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: AGR2 antibody detects endogenous levels of total AGR2. Function: Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. Promotes cell adhesion (PubMed:23274113).Subunit Structure: Monomer and homodimer (PubMed:23274113). Interacts with LYPD3 and DAG1 (alphaDAG1). Interacts with MUC2; disulfide-linked.Similarity: Belongs to the AGR family. |
Immunogen | Immunogen: A synthesized peptide derived from human AGR2 Subcellular Location: Secreted. Endoplasmic Reticulum. Tissue Specificity: Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines. Predicted Cross Reactivity: Pig, Bovine, H |
Other Names | [AG 2; AG 2 protein; AG-2; AG2; AG2 protein; AGR 2; AGR2; AGR2_HUMAN; Anterior gradient 2 homolog (Xenopus laevis); anterior gradient 2 homolog; Anterior gradient 2, protein disulphide isomerase family member; Anterior gradient 2, Xenopus, homolog of; Anterior gradient homolog 2; Anterior gradient protein 2 homolog; Epididymis secretory protein Li 116; GOB 4; GOB4; HAG 2; hAG-2; hAG2; HAG2/R; HEL S 116; HPC 8; hPC8; PDIA17; Protein disulfide isomerase family A member 17; secreted cement gland homolog; Secreted cement gland protein XAG 2 homolog; Secreted cement gland protein XAG-2 homolog; Secreted cement gland protein XAG2 homolog; XAG 2; XAG2] |
Gene, Accession # | [AGR2], Gene ID: 10551, NCBI: NP_006399.1, UniProt: O95994 |
Catalog # | MBS9608399 |
Price | $240, $280 |
Order / More Info | AGR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |