RFA2 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | RFA2 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. Through recruitment of ATRIP activates the ATR kinase a master regulator of the DNA damage response. It is required for the recruitment of the DNA double-strand break repair factors RAD51 and RAD52 to chromatin in response |
| Immunogen | n/a |
| Other Names | [Purified Mouse (Mab); Replication protein A 32 kDa subunit; RP-A p32; Replication factor A protein 2; RF-A protein 2; Replication protein A 34 kDa subunit; RP-A p34; RPA2; REPA2; RPA32; RPA34] |
| Gene, Accession # | [RPA2], Gene ID: 6118, NCBI: NP_001273005.1, UniProt: P15927 |
| Catalog # | MBS9216865 |
| Price | $165, $370 |
| Order / More Info | RFA2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Erdile L.F.,et al.J. Biol. Chem. 265:3177-3182(1990). Ebert L.,et al.Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases. Gregory S.G.,et al.Nature 441:315-321(2006). Din S.,et al.Genes Dev. 4:968-977(1990). Dutta A.,et al.EMBO J. 11:2189-2199(1992). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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