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Antigenic Specificity | Chicken CD8b |
Clone | [EP42] |
Host Species | Mouse |
Reactive Species | chicken |
Isotype | IgG2a kappa |
Format | unconjugated |
Size | 0.5 mg |
Concentration | n/a |
Applications | Flow Cytometry; Immunohistochemistry (Acetone Fixed/Frozen Sections); Immunoprecipitation |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: beta chain (Mr 34 kDa) of chicken CD8. In the chicken, the CD8 molecule is present in two forms: (i) a homodimer of two alpha chains, and (ii) a heterodimer of an alpha chain and a beta chain.1 While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8 alpha - and CD8 beta -chains, a relatively large proportion of the CD8+ TCR- gamma delta cells in the spleens of embryos and young chicks express only the alpha -chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved, but there is a population of TCR- gamma delta CD8 alpha beta cells in the chicken that is not found in rodents.3 Chicken CD8 is expressed on approximately |
Immunogen | n/a |
Other Names | [Mouse Chicken CD8b - Purified, Unlabeled; Mouse Chicken CD8 beta], [LOC100136222] |
Gene, Accession # | Gene ID: 100136222, NCBI: NP_001117480.1 |
Catalog # | MBS673902 |
Price | $305 |
Order / More Info | Chicken CD8b Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Tregaskes, C.A., F. Kong, E. Paramithiotis, C.-L. Chen, M.J.H. Ratcliffe, T. F. Davison, and J.R. Young. 1995. J. Immunol. 154:4485.2. Chan, M.L., C.-L. Chen, L. Ager, and M.D. Cooper. 1988. J. Immunol. 140:2133.3. Cooper, M.D., R.P. Bucy, and C.-L. Chen. 1990. In: The Avian Model in Developmental Biology: From Organism to Genes. Editions duCNRS, pp. 239-249.4. Ratcliffe. 1996. Personal communication. |