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Antigenic Specificity | GFRA2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total GFRA2 protein. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Synthetic peptide corresponding to a region derived from 378-392 amino acids of Human GDNF family receptor alpha 2 |
Other Names | [GDNF family receptor alpha 2, NTNRA, RETL2, TRNR2, GDNFRB, NRTNR-ALPHA] |
Gene, Accession # | [GFRA2], Gene ID: 2675, NCBI: NP_001486 |
Catalog # | MBS9413330 |
Price | $200, $255 |
Order / More Info | GFRA2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |