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Antigenic Specificity | Leptin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA Capture (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for Leptin detection. Tested with WB, IHC-P, ELISA (Cap) in Mouse; Rat.Background: Leptin have been found to be obese and diabetic and to have reduced activity, metabolism and body temperature. cDNA clones encoding Leptin have been isolated from human, simian, mouse, and rat cells. The expression of Leptin mRNA has been shown to be restricted to adipose tissue. Although regulation of fat stores is deemed to be the primary function of leptin, it also plays a role in other physiological processes, as evidenced by its multiple sites of synthesis other than fat cells, and the multiple cell types beside hypothalamic cells that have leptin recept |
Immunogen | Immunogen: E Coli-derived mouse Leptin recombinant protein (Position: V22-C167). |
Other Names | [Leptin; Obesity factor; Lep; Ob] |
Gene, Accession # | [LEP], Gene ID: 16846, NCBI: NP_032519.1, UniProt: P41160 |
Catalog # | MBS1751250 |
Price | $315 |
Order / More Info | Leptin Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK, Friedman JM (July 1995). Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269 (5223): 543-6. 2. Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y, Fei H, Kim S, Lallone R, Ranganathan S (November 1995). Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat. Med. 1 (11): 1155-61. 3. Pan H, Guo J, Su Z (May 2014). Advances in understanding the interrelations between leptin resistance and obesity.Physiology & Behavior 130: 157-169. |