TLR7 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTLR7
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionMembers of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses (1-3). TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-kappaB and subsequent regulation of immune and inflammatory genes. The TLRs and members of the IL-1 receptor family share a conserved stretch of approximately 200 amino acids known as the TIR domain. Upon activation, TLRs associate with a number of cytoplasmic adaptor proteins containing TIR domains including MyD88 (myeloid differentiation factor), MAL/TIRAP (MyD88-adaptor-like/TIR-associated protein), TRIF (Toll-receptor-associated ac
ImmunogenImmunogen: Recombinant protein of human TLR7 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[TLR7]
Gene, Accession #[TLR7], Gene ID: 51284, NCBI: NP_057646.1, UniProt: Q9NYK1
Catalog #MBS8504985
Price$310
Order / More InfoTLR7 Antibody from MYBIOSOURCE INC.
Product Specific References1. Akira, S. (2003) J Biol Chem 278, 38105-8. 2. Beutler, B. (2004) Nature 430, 257-63. 3. Dunne, A. and O'Neill, L.A. (2003) Sci STKE 2003, re3. 4. Chuang, T.H. and Ulevitch, R.J. (2000) Eur Cytokine Netw 11, 372-8. 5. Du, X. et al. (2000) Eur Cytokine Netw 11, 362-71. 6. Heil, F. et al. (2003) Eur J Immunol 33, 2987-97. 7. Hemmi, H. et al. (2002) Nat Immunol 3, 196-200. 8. Heil, F. et al. (2004) Science 303, 1526-9. 9. Diebold, S.S. et al. (2004) Science 303, 1529-31. 10. Lund, J.M. et al. (2004) Proc Natl Acad Sci USA 101, 5598-603.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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